闫尧瑶，女，1996年8月出生，校聘副教授。主要研究方向为：基于靶标的新药发现及药物化学生物学研究。近年来，以第一作者或共同第一作者身份在J. Med. Chem.、Eur. J. Med. Chem.、Bioorg. Chem.等药物化学主流期刊发表论文数篇。
1、教育背景
2018.9-2023.6 安徽医科大学 英国bet356体育在线官网 药物化学专业 医学博士
2014.9-2018.6 英国bet356体育在线官网 英国bet356体育在线官网 制药工程专业 工学学士
2、近五年主持科研项目情况
英国bet356体育在线官网高层次人才引进项目，30万，在研，主持
3、近三年发表的代表性学术论文（第一或共同第一作者）
[1].Yao Yao Yan, Xing Xing Zhang, Yun Xiao, Ming Ming Liu and Xin Hua Liu. Design and Synthesis of a 2- Amino-pyridine Derivative as a Potent CDK8 Inhibitor for Anti-colorectal Cancer Therapy [J]. Journal of medicinal chemistry,2022,65(19):13316-13239.(中科院分区药物化学一区，TOP, IF=7.3)
[2]. Yao Yao Yan, Xing Chen, Yun Xiao, Ming Ming Liu and Xin Hua Liu. Discovery and Anti-Inflammatory Activity Evaluation of a Novel CDK8 Inhibitor through Upregulation of IL-10 for the Treatment of Inflammatory Bowel Disease In Vivo[J]. Journal of medicinal chemistry, 2022,65(10):7334-7362.(中科院分区药物化学一区，TOP, IF=7.3)
[3]. Yaoyao Yan, Qi Lv, Feilong Zhou, Yujie Jian, Liu Xinhua, Xing Chen and Yong Hu. Discovery of an effective anti-inflammatory agent for inhibiting the activation of NF-κB [J]. Journal of Enzyme Inhibition and Medicinal Chemistry. 2023,38:2225135. (中科院二区，IF=5.6)
[4]. Xing Chen, Yaoyao Yan, Juncheng Du, Xiaobao Shen, Xinhua Liu. Non-peptidyl non-covalent cathepsin C inhibitorEEr bearing a unique thiophene-substituted pyridine: Design, structure-activity relationship and anti-inflammatory activity in vivo[J]. European journal of medicinal chemistry,2022,236:114368.(中科院分区药物化学一区，TOP, IF = 6.5)
[5]. Famin Zhang, Yaoyao Yan , Xu Han, Jun Cheng Du, Rende Zhu, Xin Hua Liu. Design and synthesis of the 4H-chromenone derivatives against psoriasis[J]. Bioorganic chemistry, 2022,120:105640. (中科院分区有机化学一区，TOP, IF = 5.3)
[6]. Xing Chen,Yaoyao Yan, Zhaoyan Zhang, Faming Zhang, Mingming Liu, Jing Bo Shi and Xinhua Liu. Discovery and In Vivo Anti-inflammatory Activity Evaluation of a Novel Non-peptidyl Non-covalent Cathepsin C Inhibitor[J]. Journal of medicinal chemistry, 2021,64(16):11857-11885.(中科院分区药物化学一区，TOP, IF=7.3)
4、联系方式
Email：yanyaoyao@ahtcm.edu.cn; m19956576997@163.com
